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The Benefits of Nattokinase Are Much More Than Cardiovascular

The benefits of nattokinase are many. While the cardiovascular benefits are already widely known, those for chronic inflammation, cognition and respiratory health, including asthma, rhinitis, and nasal polyps, are less so. However, recent research has shown these benefits are very real and offer much potential.

What is Nattokinase?

The story of nattokinase begins with natto, a dish deeply rooted in the traditional Japanese diet. Natto is made by steaming soybeans and fermenting them with the bacterium Bacillus subtilis. It is known for its sticky texture and unique flavour and has been consumed in Japan for centuries as a health-promoting food. The fermentation process not only enhances the nutritional profile of the soybeans but also produces nattokinase, the enzyme responsible for many of natto’s health benefits.

Dr. Hiroyuki Sumi, a Japanese researcher, discovered nattokinase in the 1980s. While studying natural fibrinolytic (fibrin-dissolving) agents, he found that natto’s enzyme had a remarkable ability to dissolve blood clots. This discovery sparked widespread interest in nattokinase as a natural alternative to synthetic clot-busting drugs, leading to further research into its broader health benefits.

Nattokinase belongs to a group of enzymes called serine proteases, which break down proteins. It plays several critical roles in the body, primarily related to its ability to break down fibrin, which is involved in not only blood clotting but also tissue repair. When fibrin accumulates excessively, it can lead to poor circulation, inflammation, and the formation of blood clots. By breaking down fibrin, nattokinase helps maintain healthy blood flow and supports the body’s natural healing processes. These unique fibrinolytic properties make it a valuable natural compound for improving circulation, reducing inflammation, and supporting overall wellness. In essence, fibrinolytic enzymes are considered antihypertensive, lipid-lowering, anti-atherosclerotic, and anti-platelet agents, which also have the benefit of demonstrating neuroprotective effects.

The Benefits of Nattokinase Are Many

The health benefits of nattokinase are diverse and backed by a growing body of research. Here are some of its most notable advantages.

As we’ve said, nattokinase helps dissolve excess fibrin, thereby improving circulation and reducing the risk of blood clots. These benefits can support heart and vascular health and may also lower the risk of stroke and heart attack. Studies have shown that nattokinase can also help reduce high blood pressure, further contributing to heart health. It can also help optimise cholesterol levels with no side effects.

Again, by targeting fibrin, which contributes to inflammation, nattokinase can help alleviate chronic inflammation, including arthritis and autoimmune disorders.

Improved circulation and reduced inflammation, in turn, help support a robust immune response and can enhance overall vitality and resilience by enabling the more efficient delivery of oxygen and nutrients throughout the body. Some promising research has even shown that nattokinase can help alleviate conditions related to BBB (blood-brain barrier) dysfunction, reduce brain inflammation, and improve cognitive ability.  This research has implications for Alzheimer’s, Parkinson’s, Huntington’s, and overall cognitive health.

Perhaps less well-known about nattokinase is its ability to reduce the viscosity of mucus and other bodily fluids, improving flow and functionality. This makes it a valuable tool for respiratory conditions, helping to clear airways and improve breathing. This lesser-known property of the enzyme is worth further examining.

The Research-Backed Benefits of Nattokinase for Rhinitis and Asthma

Chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma are common yet challenging conditions that significantly impact the quality of life. Traditional treatments often fall short. However, recent research highlights the potential of nattokinase as a novel and effective therapeutic option for these conditions.

A groundbreaking study investigated the effects of nattokinase on nasal polyps, nasal discharge, and sputum in patients with CRSwNP and asthma. It found that nattokinase could shrink nasal polyps by breaking down fibrin and reducing the viscosity of mucus in nasal discharge and sputum.

These results suggest that nattokinase addresses two critical factors in these conditions: excessive fibrin deposition and thick, sticky mucus. If mucus is too thick, it’s hard to remove, which promotes inflammation, blocked airways, difficulty breathing, and, as a result, polyp formation.

Background of the Study

CRSwNP is often comorbid with asthma and characterised by persistent inflammation, nasal obstruction, and excessive mucus production. Both conditions are notoriously resistant to treatment, making them challenging. Previous research identified excessive fibrin deposition as a key factor in forming nasal polyps.

In this study, the researchers incubated nasal polyp tissues from CRSwNP patients with nattokinase solutions at varying concentrations. They also tested the effects of nattokinase on nasal discharge and sputum from patients. The results showed significant fibrin degradation and a notable reduction in mucus viscosity, indicating the enzyme’s dual action on inflammation and mucus clearance.

In summary, nattokinase effectively breaks down fibrin in nasal polyp tissues, leading to a measurable reduction in polyp size. The enzyme also significantly reduced mucus thickness, improving airflow and alleviating symptoms in CRSwNP and asthma patients.

The study concluded that nattokinase could be a promising alternative treatment for CRSwNP and comorbid asthma.

These findings highlight the potential of nattokinase as a natural remedy for respiratory conditions. By addressing the root causes of nasal polyps and mucus buildup, nattokinase offers a holistic approach to managing symptoms and improving quality of life.

Conclusion

Nattokinase is a remarkable enzyme with wide-ranging health benefits. Its ability to break down fibrin and reduce inflammation has made it a popular choice for supporting cardiovascular health. However, its potential doesn’t stop there. More recent research has demonstrated its effectiveness in addressing respiratory conditions like rhinitis and asthma. This offers hope for patients with chronic, treatment-resistant symptoms. Further research is offering promise for blood-brain barrier conditions and cognitive health.

Nattokinase is a natural health solution that demonstrates the power of nature and science. Whether used to promote better circulation, reduce inflammation, or improve respiratory function, this enzyme is a versatile and valuable addition to a wellness protocol. As research continues to uncover new applications, nattokinase is poised to play an increasingly important role in natural health therapies.

Nattokinase bottle and refill pouch

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Sea Buckthorn: ‘The Most Perfect Plant in the Whole World’

What is sea buckthorn? 

Since the formation of the Himalayas, sea buckthorn has withstood the harsh weather conditions of the Tibetan highlands. This resilient plant yields exceptionally nutritious bright orange berries on its thorny branches. Renowned for containing over 190 bioactive nutrients crucial for health, sea buckthorn has received the accolade of the “Most Perfect Plant in the Whole World.” 

The botanical name, Hippophae rhamnoides, means “The Shiny Horse.” According to ancient legend, debilitated war horses were released into sea buckthorn forests to roam freely. They were remarkably robust and healthy when they returned with glossy, radiant coats. According to Mongol tradition, Genghis Khan attributed his armies’ remarkable strength, endurance and conquests to sea buckthorn. 

What makes sea buckthorn so good?

Plant oils usually have a complex network of nutrients. Sea buckthorn oil is considered outstanding in this regard. It contains omegas 3, 7, 6 & 9, natural vitamin E and a vast array of other nutrients. In fact, it’s an antioxidant powerhouse of vitamins and minerals. It has a unique nutritional composition of phytonutrients and potent antioxidants. It includes SOD (Superoxide Dismutase), Vitamin A, and Vitamin C, along with carotenoids, tocopherols, phytosterols, phospholipids, anti-inflammatory compounds such as ellagic acid, folic acid, ferulic acid, tannins, flavonoids including quercetin, kaempferol, isorhamnetin, and more. 

One notable feature of sea buckthorn is its high content of Omega 7. Omega 7 is a less widely recognised fatty acid renowned for its health, wellness, and cosmetic applications. It has shown promise for maintaining healthy cholesterol levels and blood sugar levels. It can help smooth artery passages and help keep artery walls strong. In addition, Omega 7 has the potential to support cellular health, provide moisture, and soothe the digestive system. It has also gained popularity as a key ingredient in beauty, skincare and anti-ageing products. Despite being present in certain fish and nuts, sea buckthorn berries stand out as a richer source of Omega 7. 

Balance the omegas

Omega-3 and omega-6 are essential fatty acids, meaning your body needs them but cannot make them naturally. However, a balanced intake between the two is considered essential. The consumption of vegetable oils high in omega-6 has increased dramatically in the past 100 years. Research indicates a high intake of omega-6 relative to omega-3 may cause issues, particularly for heart health and several chronic diseases. 

A pre-industrial diet typically maintained an omega-6 to omega-3 ratio ranging from approximately 4:1 to 1:4. By contrast, a typical Western diet today has been estimated to average a ratio of 16:1 and can go much higher. Sea buckthorn, however, maintains a naturally balanced omega 3:6 ratio, approximating a ratio of 1:1. This makes it a healthy choice to help redress these imbalances. 

Oily fish such as salmon, herring, mackerel, and sardines, fish oil and flaxseed oil, flaxseeds, walnuts, and chia seeds are all excellent sources of omega-3. And, of course, so is sea buckthorn. Processed seeds and nut oils are all sources of omega-6, and the increasing prevalence of these products in the diet is one of the reasons for the significant increase in the ratios. 

What health issues is sea buckthorn helpful for, and why

So, what are the particular benefits of this highly nutritious plant? As you might guess, with so many nutrients in one product, the issues it can assist are many and varied. 

Sea-buckthorn oil can contribute to enhanced blood circulation. It can also help promote skin oxygenation and facilitate the elimination of excess toxins from the body.  

Because it can help bring moisture into the cells, as well as being rich in unsaturated fat, antioxidants, phytosterols, carotenoids, and vitamins E and K, sea buckthorn is helpful as a beauty product. It can protect the skin’s integrity, promote its renewal and help dehydrated skin as well as wrinkles and fine lines. Its impact is further realised within the skin, where gamma-linolenic acid is converted to prostaglandins. This offers protection against infections, allergy prevention, inflammation reduction, and inhibition of the ageing process. It may also help repair damaged hair and restore its elasticity and smoothness. Maybe the legend of the ‘shiny horses’ isn’t such a legend after all!  

Mucous membranes play a pivotal role in moisture regulation. However, they are susceptible to oxidative stress from free radicals, leading to inflammation and dryness. Sea buckthorn’s diverse nutrients are essential for the upkeep of the mucous membrane cells. These cells line sensitive areas of the body, such as the eyes, digestive system, and genital regions. For this reason, sea buckthorn can be helpful for conditions like dry eyes, dry mouth and intimate dryness around menopause.

Sea buckthorn provides potential support for cardiovascular health and diabetes

Sea buckthorn oil has the potential to support cardiovascular health by mitigating blood pressure, enhancing cholesterol profiles, and offering protection against the formation of blood clots. It also exhibits the potential to enhance insulin secretion, which in turn helps to improve insulin sensitivity and regulate blood sugar levels, factors that may contribute to protection against the onset of type 2 diabetes. 

The high flavonoid and antioxidant content may help the immune system, while healthy fats, vitamin E, and carotenoids may protect liver cells from damage. 

Sea buckthorn offers some possible anticancer effects due to its bioactive compounds, such as flavonoids and antioxidants. Notably, sea buckthorn is particularly abundant in quercetin, a flavonoid that research has demonstrated properties conducive to inhibiting cancer cell proliferation. 

Conclusion

Sea buckthorn, often considered “The Most Perfect Plant in the Whole World”, provides over 190 bioactive nutrients significant for health and beauty. Its wide array of beneficial properties, including antioxidant and antibacterial, demonstrate its importance for natural health and potentially valuable impact on cardiovascular health, immune support, skin quality, and overall well-being. Sea Buckthorn’s unique omega-rich composition distinguishes it as a powerful botanical resource.

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Varicose veins – Prevention is Not in Vain

Varicose veins are very common, impacting around 25% of women and 15% of men aged 15 years and above. Often dismissed as merely concerning because of their appearance, they can indicate other health issues and require serious attention.

Comprising twisted, enlarged veins, varicose veins usually occur on the legs and feet because of the effect of gravity. Spider veins are a milder, smaller type of varicose veins, so-called because they often look like a spider web. They appear red or blue and commonly occur on the face and legs, just under the skin.

When veins are healthy, they ensure that blood flows smoothly to the heart. They prevent blood from flowing backwards using a series of tiny valves, similar to the locks in a canal. However, if those valves become damaged or weakened, blood can flow back again and collect at the lower valve. This can then lead to a build-up of blood, causing the vein to swell.

Any vein near the skin’s surface can become varicose, resulting in aching, heavy and uncomfortable legs, swollen feet and ankles, and burning or throbbing. There can be cramping, especially at night, and the skin over the veins can become dry, thin and itchy.

Risk factors for developing varicose veins include pregnancy and obesity, which put added pressure on veins, wear and tear from ageing, and standing or sitting for long periods. Women tend to develop varicose veins more than men, which may be because female hormones can relax vein walls.

Though they are considered more common than heart and peripheral arterial disease combined, varicose veins are generally underdiagnosed and undertreated. And whilst complications are rare, there is still a chance of inflammation, ulcers, or blood clots forming, so it makes sense to minimise that risk by improving blood flow and muscle tone.

Ways to help improve varicose veins 

Adopting a balanced diet rich in antioxidants and nutrients contributes to overall health. Foods like berries, citrus fruits, and leafy greens provide the body with essential vitamins and minerals.

Proper hydration supports overall circulatory health by maintaining vein elasticity. Drinking adequate water throughout the day helps ensure that blood can flow smoothly through the veins.

Regular exercise, particularly activities like walking, swimming, tai chi, or yoga, supports circulation and can also help manage weight, reducing the burden on veins.

Avoiding prolonged periods of sitting or standing is crucial for preventing varicose veins. Changing positions regularly is vital for encouraging blood flow. Short breaks to move and stretch throughout the day keep blood circulating and reduce the risk of developing or worsening varicose veins. Elevating the legs, especially after a long day, can relieve pressure on veins and encourage blood to flow back towards the heart.

Avoid over-tight hosiery, which can limit circulation. However, well-fitting compression socks or stockings can provide beneficial external support, aiding proper blood circulation and reducing the symptoms associated with varicose veins.

Is it time to ditch the heels?

Choose footwear that prioritises comfort and support. High heels move the weight to the fore of the foot and the toes, causing the calf muscles to remain contracted. As a result, the foot and calf veins do not fill as well, and the calf muscle pump is less forceful.

Why is this so important? Veins carry deoxygenated blood back to the heart. In the legs, superficial veins located just below the skin surface collect blood. Deeper veins that run within the calf muscles then receive the blood. The calves’ muscular action helps pump the blood against the force of gravity towards the heart, and one-way valves inside the veins prevent the blood from travelling backwards. If this pumping action is compromised, the resultant lowering of efficiency can cause the pooling of blood in the leg and result in varicose veins.

You can consider several supplements when looking to help and maintain venous health.

Vitamin C plays a crucial role in collagen formation and is the building block of veins and blood vessels. One containing bioflavonoids would be a good choice, as these are known to enhance its efficacy. A healthy daily dose may even help restore those stubborn veins.

Various proteolytic enzymes have anti-inflammatory properties that may help reduce inflammation associated with varicose veins. Enzymes, such as bromelain, papain, and trypsin, for example, are useful to help support blood vessel health.

Curcumin, the active compound in turmeric, is known for its anti-inflammatory and antioxidant properties, contributing to overall vein health. When taken together, amino acids like l-arginine and l-lysine boost nitric oxide production, improving blood circulation.

Conclusion

Varicose veins may be a common concern, but a holistic approach involving natural remedies can often contribute to prevention as well as relief. You can promote optimal vein health by adopting a healthy lifestyle, incorporating targeted supplements, and staying mindful of risk factors. Natural approaches are often gradual in their effects, so consistency and patience are key when adopting these strategies.

 

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